2GM1
Crystal structure of the mitotic kinesin eg5 in complex with mg-adp and n-(3-aminopropyl)-n-((3-benzyl-5-chloro-4-oxo-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)(cyclopropyl)methyl)-4-methylbenzamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, E) | KINESIN-RELATED MOTOR PROTEIN EG5 | polymer | 368 | 41055.6 | 4 | UniProt (P52732) Pfam (PF00225) | Homo sapiens (human) | |
| 2 | E, F, I, J, M... (A, B, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 3 | G, K, O, S (A, B, D, E) | N-(3-AMINOPROPYL)-N-[(R)-(3-BENZYL-5-CHLORO-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)(CYCLOPROPYL)METHYL]-4-METHYLBENZAMIDE | non-polymer | 504.0 | 4 | Chemie (2AZ) | |||
| 4 | H, L, P, T (A, B, D, E) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 5 | U, V, W, X (A, B, D, E) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164222.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3919.3 | |
| All* | Total formula weight | 168141.7 |
