2GL7
Crystal Structure of a beta-catenin/BCL9/Tcf4 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Beta-catenin | polymer | 550 | 60240.7 | 2 | UniProt (P35222) Pfam (PF00514) | Homo sapiens (human) | |
| 2 | B, E (B, E) | Transcription factor 7-like 2 | polymer | 53 | 5632.8 | 2 | UniProt (Q9NQB0) | Homo sapiens (human) | HMG box transcription factor 4, T- cell-specific transcription factor 4, TCF-4, hTCF-4 |
| 3 | C, F (C, F) | B-cell lymphoma 9 protein | polymer | 46 | 5285.7 | 2 | UniProt (O00512) Pfam (PF11502) | Homo sapiens (human) | Bcl-9, Legless homolog |
| 4 | G, H, I, J (A, B, D, E) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, D: 138 - 686 (UniProt: P35222)
| PDB | External Database | Details |
|---|---|---|
| Ser 137 | - | cloning artifact |
| Glu 142 | Tyr 142 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 142318.4 | |
| All* | Total formula weight | 142318.4 |
