2GL7
Crystal Structure of a beta-catenin/BCL9/Tcf4 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Beta-catenin | polymer | 550 | 60240.7 | 2 | UniProt (P35222) Pfam (PF00514) In PDB | Homo sapiens (human) | |
2 | B, E | Transcription factor 7-like 2 | polymer | 53 | 5632.8 | 2 | UniProt (Q9NQB0) In PDB | Homo sapiens (human) | HMG box transcription factor 4, T- cell-specific transcription factor 4, TCF-4, hTCF-4 |
3 | C, F | B-cell lymphoma 9 protein | polymer | 46 | 5285.7 | 2 | UniProt (O00512) Pfam (PF11502) In PDB | Homo sapiens (human) | Bcl-9, Legless homolog |
4 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, D: 138 - 686 (UniProt: P35222)
PDB | External Database | Details |
---|---|---|
Ser 137 | - | cloning artifact |
Glu 142 | Tyr 142 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 142318.4 | |
All* | Total formula weight | 142318.4 |