2GJ7
Crystal Structure of a gE-gI/Fc complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Ig gamma-1 chain C region | polymer | 227 | 25611.0 | 2 | UniProt (P01857) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B, D (F, E) | Glycoprotein E | polymer | 401 | 42996.3 | 2 | UniProt (P04488) Pfam (PF20418) Pfam (PF02480) | Human herpesvirus 1 | |
| 3 | E, F (C, D) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1422.3 | 2 | In PDB GlyTouCan (G61334IA) |
Sequence modifications
A, B: 223 - 447 (UniProt: P01857)
F, E: 21 - 419 (UniProt: P04488)
| PDB | External Database | Details |
|---|---|---|
| Leu 221 | - | cloning artifact |
| Glu 222 | - | cloning artifact |
| Glu 356 | Asp 239 | conflict |
| Met 358 | Leu 241 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Asp 420 | - | cloning artifact |
| Ile 421 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 137214.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2844.6 | |
| All* | Total formula weight | 140059.1 |
