2GIV

Human MYST histone acetyltransferase 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Probable histone acetyltransferase MYST1	polymer	295	34458.6	1	GenBank (14149875) Pfam (PF17772) Pfam (PF01853) UniProt (by SIFTS) (Q9H7Z6)	Homo sapiens (human)	MYST protein 1, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, hMOF
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL) PubChem (312)
4	D (A)	ACETYL COENZYME *A	non-polymer		809.6	1	Chemie (ACO) PubChem (25210474) PubChem (24860528) PubChem (53393727) PubChem (56846401) PubChem (44141873) PubChem (45254004) PubChem (444493) PubChem (53245716) PubChem (87656764) PubChem (181) PubChem (6302) PubChem (87656765) PubChem (89102998) PubChem (91746285) PubChem (6857822) PubChem (6917106) PubChem (134956084) PubChem (10079099) PubChem (124511019) PubChem (11987898) PubChem (16061174) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977)
5	E (A)	water	water		18.0	185	Chemie (HOH)

Sequence modifications

A: 1 - 276 (GenBank: 14149875)

PDB	External Database	Details
Aly 101	Lys 274	modified residue
Met -18	-	initiating methionine
Gly -17	-	cloning artifact
Ser -16	-	cloning artifact
Ser -15	-	cloning artifact
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	cloning artifact
Ser -7	-	cloning artifact
Gly -6	-	cloning artifact
Leu -5	-	cloning artifact
Val -4	-	cloning artifact
Pro -3	-	cloning artifact
Arg -2	-	cloning artifact
Gly -1	-	cloning artifact
Ser 0	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34458.6
Non-Polymers*	Number of molecules	3
	Total formula weight	910.4
All*	Total formula weight	35369.1

*Water molecules are not included.