2GHQ

CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	polymer	181	20876.8	2	UniProt (Q9GZU7) Pfam (PF03031) In PDB	Homo sapiens (human)	Nuclear LIM interactor-interacting factor 3, NLI-interacting factor 3, NLI-IF
2	C, D	DNA-directed RNA polymerase II largest subunit	polymer	9	1081.9	2	UniProt (P24928) Pfam (PF05001) In PDB	Homo sapiens (human)	RPB1
3	B, C	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4		water	water		18.0	103	Chemie (HOH)

Sequence modifications

A, B: 77 - 256 (UniProt: Q9GZU7)

PDB	External Database	Details
His 76	-	cloning artifact
Asn 96	Asp 96	engineered mutation

C, D: 168 - 176 (UniProt: P24928)

PDB	External Database	Details
Sep 171	Ser 1798	modified residue
Sep 174	Ser 1801	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	43917.3
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	43965.9

*Water molecules are not included.