2GHQ
CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | polymer | 181 | 20876.8 | 2 | UniProt (Q9GZU7) Pfam (PF03031) | Homo sapiens (human) | Nuclear LIM interactor-interacting factor 3, NLI-interacting factor 3, NLI-IF |
| 2 | C, D (C, D) | DNA-directed RNA polymerase II largest subunit | polymer | 9 | 1081.9 | 2 | UniProt (P24928) Pfam (PF05001) | Homo sapiens (human) | RPB1 |
| 3 | E, F (B, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B: 77 - 256 (UniProt: Q9GZU7)
C, D: 168 - 176 (UniProt: P24928)
| PDB | External Database | Details |
|---|---|---|
| His 76 | - | cloning artifact |
| Asn 96 | Asp 96 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Sep 171 | Ser 1798 | modified residue |
| Sep 174 | Ser 1801 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43917.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 43965.9 |
