2GFE

Crystal structure of the GluR2 A476E S673D Ligand Binding Core Mutant at 1.54 Angstroms Resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Glutamate receptor 2	polymer	262	29220.7	3	UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB	Rattus norvegicus (Norway rat)	GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2
2	A, B, C	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
3	A, B, C	GLUTAMIC ACID	non-polymer		147.1	3	Chemie (GLU)
4		water	water		18.0	746	Chemie (HOH)

Sequence modifications

A, B, C: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Gly 1	-	cloning artifact
Ala 2	-	cloning artifact
Glu 66	Ala 476	engineered mutation

A, B, C: 120 - 262 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Asp 140	Ser 673	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	87662.0
Non-Polymers*	Number of molecules	8
	Total formula weight	768.4
All*	Total formula weight	88430.4

*Water molecules are not included.