2G9H
Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HLA class II histocompatibility antigen, DR alpha chain | polymer | 182 | 21155.9 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | MHC class II antigen DRA |
2 | B | HLA class II histocompatibility antigen, DRB1-1 beta chain | polymer | 190 | 22080.7 | 1 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB | Homo sapiens (human) | MHC class I antigen DRB1*1, DR-1, DR1 |
3 | C | Hemagglutinin | polymer | 13 | 1506.8 | 1 | UniProt (P04664) In PDB | ||
4 | D | extracellular enterotoxin type I | polymer | 218 | 24962.0 | 1 | UniProt (O85383) Pfam (PF01123) Pfam (PF02876) UniProt (by SIFTS) (Q52T95) In PDB | Staphylococcus aureus | |
5 | A, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
6 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
7 | A | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 2 | Chemie (DIO) | |||
8 | D | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
9 | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence modifications
D: 1 - 218 (UniProt: O85383)
PDB | External Database | Details |
---|---|---|
Leu 24 | Val 48 | SEE REMARK 999 |
Ile 25 | Thr 49 | SEE REMARK 999 |
Ser 31 | Ile 55 | SEE REMARK 999 |
Ile 41 | Thr 65 | SEE REMARK 999 |
Ser 114 | Ala 138 | SEE REMARK 999 |
Ser 144 | Asn 168 | SEE REMARK 999 |
Lys 163 | Asn 187 | SEE REMARK 999 |
Asp 172 | Asn 196 | SEE REMARK 999 |
Val 187 | Leu 211 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 69705.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 864.2 | |
All* | Total formula weight | 70569.6 |