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2G97

Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Nicotinamide phosphoribosyltransferasepolymer49155512.72UniProt (Q80Z29)
Pfam (PF18127)
Pfam (PF04095)
Rattus norvegicus (Norway rat)NAmPRTase, Nampt, Pre-B-cell colony-enhancing factor 1 homolog, PBEF, Visfatin
2C, D
(A, B)
(2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamidenon-polymer391.52Chemie (DGB)
3E, F
(A, B)
waterwater18.0117Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111025.4
Non-Polymers*Number of molecules2
Total formula weight783.0
All*Total formula weight111808.4
*Water molecules are not included.

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PDB entries from 2025-12-10

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