2G78
Crystal Structure of the R132K:Y134F Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinoic Acid at 1.70 Angstroms Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular retinoic acid-binding protein 2 | polymer | 137 | 15537.8 | 1 | UniProt (P29373) Pfam (PF00061) | Homo sapiens (human) | Cellular retinoic acid- binding protein II, CRABP-II, Retinoic acid-binding protein II, cellular |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 3 | C (A) | RETINOIC ACID | non-polymer | 300.4 | 1 | Chemie (REA) PubChem (5538) PubChem (23275881) PubChem (25145416) PubChem (444795) PubChem (449171) PubChem (5282379) PubChem (6336207) PubChem (6336229) PubChem (6419708) PubChem (87179195) PubChem (87519764) PubChem (87980058) PubChem (88439848) PubChem (88525859) PubChem (88604688) PubChem (6603983) PubChem (9796370) PubChem (9861147) PubChem (445925) PubChem (10881132) PubChem (12358677) PubChem (12358678) PubChem (12358679) PubChem (12358681) PubChem (134688661) PubChem (139597075) PubChem (145826768) PubChem (166478803) | |||
| 4 | D (A) | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
A: 1 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Lys 132 | Arg 132 | engineered mutation |
| Phe 134 | Tyr 134 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15537.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 323.4 | |
| All* | Total formula weight | 15861.2 |
