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2G5P

Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ac

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BDipeptidyl peptidase 4polymer72684252.32UniProt (P27487)
Pfam (PF00930)
Pfam (PF00326)
In PDB
Homo sapiens (human)Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, Adenosine deaminase complexing protein 2, ADABP, Contains: Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form
2A4-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-3-TERT-BUTYLBENZOIC ACIDnon-polymer403.51Chemie (ADF)
3waterwater18.01599Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight168504.7
Non-Polymers*Number of molecules1
Total formula weight403.5
All*Total formula weight168908.2
*Water molecules are not included.

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PDB entries from 2024-09-11

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