2G28

E. Coli Pyruvate Dehydrogenase H407A variant Phosphonolactylthiamin Diphosphate Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Pyruvate dehydrogenase E1 component	polymer	886	99657.2	2	UniProt (P0AFG8) Pfam (PF00456) Pfam (PF17831) Pfam (PF22613)	Escherichia coli
2	C, E (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	D, F (A, B)	3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM	non-polymer		563.4	2	Chemie (TDK)
4	G, H (A, B)	water	water		18.0	549	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	199314.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1175.4
All*	Total formula weight	200489.7

*Water molecules are not included.