2G27

Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Renin	polymer	333	36566.2	2	UniProt (P00797) Pfam (PF00026)	Homo sapiens (human)	Angiotensinogenase
2	C, D (A, B)	METHYL (6-{[(2R)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)-6-OXOPIPERAZIN-2-YL]METHOXY}-1H-INDOL-1-YL)ACETATE	non-polymer		587.7	2	Chemie (4LG)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73132.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1175.3
All*	Total formula weight	74307.8

*Water molecules are not included.