2G0H
Structure-based drug design of a novel family of PPAR partial agonists: virtual screening, x-ray crystallography and in vitro/in vivo biological activities
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 271 | 30997.0 | 2 | UniProt (Q86U60) Pfam (PF00104) UniProt (by SIFTS) (P37231) | Homo sapiens (human) | PPAR-gamma |
| 2 | C, D (A, B) | N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]-3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONAMIDE | non-polymer | 535.5 | 2 | Chemie (SP3) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61994.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1070.9 | |
| All* | Total formula weight | 63065.0 |
