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2FZE

Crystal structure of the binary complex of human glutathione-dependent formaldehyde dehydrogenase with ADP-ribose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Alcohol dehydrogenase class III chi chainpolymer37339641.02UniProt (P11766)
Pfam (PF08240)
Pfam (PF00107)
Homo sapiens (human)S- hydroxymethyl, glutathione dehydrogenase, Glutathione- dependent formaldehyde dehydrogenase, FDH
2C, D, I, J
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
3E, K
(A, B)
POTASSIUM IONnon-polymer39.12Chemie (K)
4F, G, L
(A, B)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
5H, M
(A, B)
ADENOSINE-5-DIPHOSPHORIBOSEnon-polymer559.32Chemie (APR)
6N, O
(A, B)
waterwater18.01006Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight79282.0
Non-Polymers*Number of molecules11
Total formula weight1743.4
All*Total formula weight81025.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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