2FZD
Human aldose reductase complexed with tolrestat at 1.08 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | aldose reductase | polymer | 316 | 35898.3 | 1 | UniProt (Q5U031) Pfam (PF00248) UniProt (by SIFTS) (P15121) | Homo sapiens (human) | |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C (A) | TOLRESTAT | non-polymer | 357.3 | 1 | Chemie (TOL) | |||
| 4 | D (A) | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35898.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1100.8 | |
| All* | Total formula weight | 36999.1 |
