2FX7
Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | Fab 4E10 | polymer | 214 | 23292.7 | 1 | Homo sapiens (human) | ||
2 | H | Fab 4E10 | polymer | 228 | 23990.0 | 1 | Homo sapiens (human) | ||
3 | P | Fragment of HIV glycoprotein (GP41) | polymer | 16 | 2187.6 | 1 | UniProt (P05880) In PDB | ||
4 | L | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
P: 671 - 686 (UniProt: P05880)
PDB | External Database | Details |
---|---|---|
Lys 684 | Ile 675 | engineered mutation |
Lys 685 | Phe 676 | engineered mutation |
Lys 686 | Ile 677 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 49470.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 49562.4 |