2FVJ
A novel anti-adipogenic partial agonist of peroxisome proliferator-activated receptor-gamma (PPARG) recruits pparg-coactivator-1 alpha (PGC1A) but potentiates insulin signaling in vitro
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 271 | 30997.0 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 13 | 1471.7 | 1 | UniProt (Q15788) | Homo sapiens (human) | NCoA-1, Steroid receptor coactivator-1, SRC-1, RIP160, Hin-2 protein |
| 3 | C (A) | 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-4-{[4-(2-METHOXYPHENYL)PIPERIDIN-1-YL]METHYL}ISOQUINOLINE | non-polymer | 542.7 | 1 | Chemie (RO0) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32468.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 634.8 | |
| All* | Total formula weight | 33103.5 |
