2FT2
Human Cathepsin S with Inhibitor CRA-29728
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | cathepsin S | polymer | 225 | 25006.0 | 2 | UniProt (P25774) Pfam (PF00112) In PDB | Homo sapiens (human) | |
| 2 | A, B | N-[1-(AMINOMETHYL)CYCLOPROPYL]-3-(MORPHOLIN-4-YLSULFONYL)-N~2~-[(1S)-2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL)ETHYL]-L-ALANINAMIDE | non-polymer | 482.5 | 2 | Chemie (C28) | |||
| 3 | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 218 (UniProt: P25774)
| PDB | External Database | Details |
|---|---|---|
| Gly 219 | - | CLONING ARTIFACT |
| His 220 | - | CLONING ARTIFACT |
| His 221 | - | CLONING ARTIFACT |
| His 222 | - | CLONING ARTIFACT |
| His 223 | - | CLONING ARTIFACT |
| His 224 | - | CLONING ARTIFACT |
| His 225 | - | CLONING ARTIFACT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50012.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 965.0 | |
| All* | Total formula weight | 50977.0 |
