Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE C28 A 999 |
Chain | Residue |
A | GLN19 |
A | PHE67 |
A | MET68 |
A | GLY133 |
A | ASN158 |
A | HIS159 |
A | GLY160 |
A | HOH1103 |
A | GLY23 |
A | CYS25 |
A | TRP26 |
A | GLY59 |
A | LYS61 |
A | ASN64 |
A | GLY65 |
A | GLY66 |
site_id | AC2 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE C28 B 998 |
Chain | Residue |
B | GLN19 |
B | GLY23 |
B | CYS25 |
B | TRP26 |
B | GLY59 |
B | LYS61 |
B | ASN64 |
B | GLY65 |
B | GLY66 |
B | PHE67 |
B | MET68 |
B | GLY133 |
B | ASN158 |
B | HIS159 |
B | GLY160 |
Functional Information from PROSITE/UniProt
site_id | PS00139 |
Number of Residues | 12 |
Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGACWAfSA |
Chain | Residue | Details |
A | GLN19-ALA30 | |
site_id | PS00639 |
Number of Residues | 11 |
Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHGVLVVGYG |
Chain | Residue | Details |
A | VAL157-GLY173 | |
site_id | PS00640 |
Number of Residues | 20 |
Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWghnFGeeGYIrM |
Chain | Residue | Details |
A | TYR174-MET199 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | ACT_SITE: ACT_SITE => ECO:0000250 |
Chain | Residue | Details |
A | CYS25 | |
A | HIS159 | |
A | ASN175 | |
B | CYS25 | |
B | HIS159 | |
B | ASN175 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
A | ASN175 | |
A | CYS25 | |
A | HIS159 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
B | ASN175 | |
B | CYS25 | |
B | HIS159 | |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
A | GLN19 | |
A | CYS25 | |
A | HIS159 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
B | GLN19 | |
B | CYS25 | |
B | HIS159 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
A | ASN175 | |
A | GLN19 | |
A | HIS159 | |
site_id | CSA6 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1pad |
Chain | Residue | Details |
B | ASN175 | |
B | GLN19 | |
B | HIS159 | |
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 814 |
Chain | Residue | Details |
A | GLN19 | electrostatic stabiliser |
A | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
A | HIS159 | proton acceptor, proton donor |
A | ASN175 | electrostatic stabiliser |
site_id | MCSA2 |
Number of Residues | 4 |
Details | M-CSA 814 |
Chain | Residue | Details |
B | GLN19 | electrostatic stabiliser |
B | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
B | HIS159 | proton acceptor, proton donor |
B | ASN175 | electrostatic stabiliser |