2FS4
Ketopiperazine-Based Renin Inhibitors: Optimization of the C ring
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Renin | polymer | 333 | 36566.2 | 2 | UniProt (P00797) Pfam (PF00026) | Homo sapiens (human) | Angiotensinogenase |
| 2 | C (B) | (6R)-6-({[1-(3-HYDROXYPROPYL)-1,7-DIHYDROQUINOLIN-7-YL]OXY}METHYL)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)PIPERAZIN-2-ONE | non-polymer | 587.7 | 1 | Chemie (PZ1) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73132.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 587.7 | |
| All* | Total formula weight | 73720.2 |
