2FMA
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, atomic resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Amyloid beta A4 protein precursor | polymer | 59 | 6848.9 | 1 | UniProt (P05067) Pfam (PF12924) | Homo sapiens (human) | Amyloid Precursor Protein, Amyloid beta A4 protein, Soluble APP-alpha, Soluble APP-beta |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 133 - 189 (UniProt: P05067)
| PDB | External Database | Details |
|---|---|---|
| Glu 131 | - | cloning artifact |
| Ala 132 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 6848.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 6941.0 |
