2FKY

crystal structure of KSP in complex with inhibitor 13

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Kinesin-like protein KIF11	polymer	367	40924.4	2	UniProt (P52732) Pfam (PF00225) In PDB	Homo sapiens (human)	Kinesin-related motor protein Eg5, Kinesin-like spindle protein HKSP, Thyroid receptor interacting protein 5, TRIP5, Kinesin-like protein 1
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A, B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
4	A, B	(2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE	non-polymer		397.5	2	Chemie (N2T)
5		water	water		18.0	221	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	81848.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1697.9
All*	Total formula weight	83546.7

*Water molecules are not included.