2FIX
Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, H, L) | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36859.4 | 4 | GenBank (15277851) Pfam (PF00316) Pfam (PF18913) UniProt (by SIFTS) (P09467) | Homo sapiens (human) | |
| 2 | E, F, G, H (A, D, H, L) | N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE | non-polymer | 464.3 | 4 | Chemie (870) |
Sequence modifications
A, D, H, L: 0 - 337 (GenBank: 15277851)
| PDB | External Database | Details |
|---|---|---|
| Lys 217 | Arg 218 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147437.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1857.3 | |
| All* | Total formula weight | 149295.0 |
