2FIE
Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, H, L | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36859.4 | 4 | GenBank (15277851) Pfam (PF00316) Pfam (PF18913) UniProt (by SIFTS) (P09467) In PDB | Homo sapiens (human) | |
| 2 | A, D, H, L | 2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE | non-polymer | 480.3 | 4 | Chemie (A74) | |||
| 3 | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, D, H, L: 0 - 337 (GenBank: 15277851)
| PDB | External Database | Details |
|---|---|---|
| Lys 217 | Arg 218 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147437.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1921.3 | |
| All* | Total formula weight | 149359.0 |
