2FFY
AmpC beta-lactamase N289A mutant in complex with a boronic acid deacylation transition state analog compound SM3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Beta-lactamase | polymer | 358 | 39544.9 | 2 | UniProt (P00811) Pfam (PF00144) In PDB | Escherichia coli | Cephalosporinase |
2 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
3 | A, B | (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID | non-polymer | 275.1 | 2 | Chemie (SM3) | |||
4 | B | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
5 | water | water | 18.0 | 1114 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 361 (UniProt: P00811)
PDB | External Database | Details |
---|---|---|
Ala 289 | Asn 305 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 79089.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 723.4 | |
All* | Total formula weight | 79813.2 |