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2FAP

THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-(C16)-ETHOXY RAPAMYCIN COMPLEX INTERACTING WITH HUMA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
FK506-BINDING PROTEINpolymer10711836.51UniProt (P62942)
Pfam (PF00254)
Homo sapiens (human)FKBP12
2B
(B)
FRAPpolymer9411331.91UniProt (P42345)
Pfam (PF08771)
Homo sapiens (human)FKBP-RAPAMYCIN ASSOCIATED PROTEIN
3C
(A)
C49-METHYL RAPAMYCINnon-polymer928.21Chemie (RAD)
4D, E
(A, B)
waterwater18.0126Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight23168.4
Non-Polymers*Number of molecules1
Total formula weight928.2
All*Total formula weight24096.6
*Water molecules are not included.

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PDB entries from 2025-07-16

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