2F9O
Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant D216G
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tryptase alpha-1 | polymer | 245 | 27660.7 | 4 | UniProt (P15157) Pfam (PF00089) UniProt (by SIFTS) (Q15661) | Homo sapiens (human) | Tryptase-1 |
| 2 | E, F (E, F) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G11971MR) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 747 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 16 - 246 (UniProt: P15157)
| PDB | External Database | Details |
|---|---|---|
| Val 59 | Leu 76 | engineered mutation |
| Gly 216 | Asp 245 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110642.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| All* | Total formula weight | 111783.8 |
