2F9J
3.0 angstrom resolution structure of a Y22M mutant of the spliceosomal protein p14 bound to a region of SF3b155
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Pre-mRNA branch site protein p14 | polymer | 125 | 14574.9 | 2 | UniProt (Q9Y3B4) Pfam (PF00076) | Homo sapiens (human) | SF3B 14 kDa subunit |
| 2 | B, D (P, Q) | Splicing factor 3B subunit 1 | polymer | 36 | 4411.8 | 2 | UniProt (O75533) | Homo sapiens (human) | Spliceosome associated protein 155, SAP 155, SF3b155, Pre-mRNA splicing factor SF3b 155 kDa subunit |
| 3 | E, F, G (A, P, B) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 125 (UniProt: Q9Y3B4)
P, Q: 381 - 415 (UniProt: O75533)
| PDB | External Database | Details |
|---|---|---|
| Met 22 | Tyr 22 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 380 | - | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 37973.5 | |
| All* | Total formula weight | 37973.5 |
