2F8A

Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Glutathione peroxidase 1	polymer	208	23147.2	2	UniProt (P07203) Pfam (PF00255) In PDB	Homo sapiens (human)	GSHPx-1, GPx-1, Cellular glutathione peroxidase
2	A, B	MALONIC ACID	non-polymer		104.1	2	Chemie (MLA)
3		water	water		18.0	409	Chemie (HOH)

Sequence modifications

A, B: 12 - 196 (UniProt: P07203)

PDB	External Database	Details
Met -22	-	cloning artifact
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	cloning artifact
Ser -14	-	cloning artifact
Gly -13	-	cloning artifact
Val -12	-	cloning artifact
Asp -11	-	cloning artifact
Leu -10	-	cloning artifact
Gly -9	-	cloning artifact
Thr -8	-	cloning artifact
Glu -7	-	cloning artifact
Asn -6	-	cloning artifact
Leu -5	-	cloning artifact
Tyr -4	-	cloning artifact
Phe -3	-	cloning artifact
Gln -2	-	cloning artifact
Ser -1	-	cloning artifact
Met 0	-	cloning artifact
Gly 47	Cys 47	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46294.5
Non-Polymers*	Number of molecules	2
	Total formula weight	208.1
All*	Total formula weight	46502.6

*Water molecules are not included.