2F2L
Crystal structure of tracheal cytotoxin (TCT) bound to the ectodomain complex of peptidoglycan recognition proteins LCa (PGRP-LCa) and LCx (PGRP-LCx)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidoglycan-recognition protein-LC isoform LCa | polymer | 167 | 18717.3 | 1 | UniProt (Q9GNK5) Pfam (PF01510) UniProt (by SIFTS) (Q8SXQ7) | Drosophila melanogaster (fruit fly) | Immune response deficient 7 protein |
| 2 | B (X) | Peptidoglycan recognition protein-LC isoform LCx | polymer | 167 | 19072.7 | 1 | GenBank (20271150) Pfam (PF01510) UniProt (by SIFTS) (Q9GNK5) | Drosophila melanogaster (fruit fly) | |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (A) | 2-acetylamino-2-deoxy-alpha-L-idopyranose | non-polymer | 221.2 | 1 | Chemie (HSQ) | |||
| 5 | E, F (A, X) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | G (X) | GLCNAC(BETA1-4)-MURNAC(1,6-ANHYDRO)-L-ALA-GAMMA-D-GLU-MESO-A2PM-D-ALA | non-polymer | 921.9 | 1 | Chemie (MLD) | |||
| 7 | H (X) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 8 | I, J (A, X) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A: 355 - 520 (UniProt: Q9GNK5)
X: 335 - 500 (GenBank: 20271150)
| PDB | External Database | Details |
|---|---|---|
| Asp 354 | - | cloning artifact |
| Cso 414 | Cys 414 | modified residue |
| PDB | External Database | Details |
|---|---|---|
| Met 334 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37790.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1748.6 | |
| All* | Total formula weight | 39538.6 |
