2F2C
X-ray structure of human CDK6-Vcyclinwith the inhibitor aminopurvalanol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin homolog | polymer | 254 | 28665.4 | 1 | UniProt (Q01043) Pfam (PF00134) Pfam (PF09241) | Herpesvirus saimiri (strain 11) | V-cyclin |
| 2 | B (B) | Cell division protein kinase 6 | polymer | 308 | 35066.3 | 1 | UniProt (Q00534) Pfam (PF00069) | Homo sapiens (human) | Serine/threonine-protein kinase PLSTIRE |
| 3 | C (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (B) | (2S)-2-({6-[(3-AMINO-5-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL | non-polymer | 403.9 | 1 | Chemie (AP9) | |||
| 5 | E (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63731.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 578.1 | |
| All* | Total formula weight | 64309.9 |
