2F28
Crystal Structure of the Human Sialidase Neu2 Q116E Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sialidase 2 | polymer | 382 | 42420.6 | 1 | UniProt (Q9Y3R4) Pfam (PF13088) | Homo sapiens (human) | Neu2, Cytosolic sialidase, N-acetyl-alpha- neuraminidase 2 |
| 2 | B, C (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D (A) | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence modifications
A: 1 - 380 (UniProt: Q9Y3R4)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Glu 116 | Gln 116 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42420.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 42491.5 |
