2F0A

Crystal Structure of Monomeric Uncomplexed form of Xenopus dishevelled PDZ domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Segment polarity protein dishevelled homolog DVL-2	polymer	98	11002.8	4	UniProt (P51142) Pfam (PF00595)	Xenopus laevis (African clawed frog)	Dishevelled-2, DSH homolog 2, Xdsh
2	E (B)	COBALT (II) ION	non-polymer		58.9	1	Chemie (CO)
3	F (D)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	G, H, I, J (A, B, C, D)	water	water		18.0	152	Chemie (HOH)

Sequence modifications

A, B, C, D: 252 - 340 (UniProt: P51142)

PDB	External Database	Details
Mse 251	-	initiating methionine
Mse 259	Met 259	modified residue
Mse 287	Met 287	modified residue
Mse 303	Met 303	modified residue
Mse 315	Met 315	modified residue
Leu 341	-	cloning artifact
Glu 342	-	cloning artifact
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	44011.2
Non-Polymers*	Number of molecules	2
	Total formula weight	155.0
All*	Total formula weight	44166.2

*Water molecules are not included.