2EXL

GRP94 N-terminal Domain bound to geldanamycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Endoplasmin	polymer	236	26514.0	2	UniProt (P41148) Pfam (PF13589)	Canis lupus familiaris (dog)	94 kDa glucose-regulated protein, GRP94
2	C, G (A, B)	GELDANAMYCIN	non-polymer		560.6	2	Chemie (GDM)
3	D, E, H, I (A, B)	TETRAETHYLENE GLYCOL	non-polymer		194.2	4	Chemie (PG4)
4	F (A)	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
5	J, K (A, B)	water	water		18.0	282	Chemie (HOH)

Sequence modifications

A, B: 69 - 286 (UniProt: P41148)

PDB	External Database	Details
Gly 65	-	cloning artifact
Ser 66	-	cloning artifact
His 67	-	cloning artifact
Met 68	-	cloning artifact

A, B: 328 - 337 (UniProt: P41148)

PDB	External Database	Details
Gly 324	-	SEE REMARK 999
Gly 325	-	SEE REMARK 999
Gly 326	-	SEE REMARK 999
Gly 327	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53028.0
Non-Polymers*	Number of molecules	7
	Total formula weight	2136.5
All*	Total formula weight	55164.5

*Water molecules are not included.