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2EXC

Inhibitor complex of JNK3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(X)
Mitogen-activated protein kinase 10polymer35641180.61UniProt (P53779)
Pfam (PF00069)
Homo sapiens (human)Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, MAP kinase p49 3F12
2B
(X)
N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDEnon-polymer420.51Chemie (JNK)
3C
(X)
waterwater18.085Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41180.6
Non-Polymers*Number of molecules1
Total formula weight420.5
All*Total formula weight41601.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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