2EXB
Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, complexed with FLOMOX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Penicillin-binding protein 4 | polymer | 458 | 49796.7 | 1 | UniProt (P24228) Pfam (PF02113) | Escherichia coli | |
| 2 | B (A) | 2,2-dimethylpropanoyloxymethyl (2R)-5-(aminocarbonyloxymethyl)-2-[(1R)-1-[[(Z)-2-(2-azanyl-1,3-thiazol-4-yl)pent-2-enoyl]amino]-2-oxidanylidene-ethyl]- 3,6-dihydro-2H-1,3-thiazine-4-carboxylate | non-polymer | 569.7 | 1 | Chemie (FXM) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A: 21 - 477 (UniProt: P24228)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | initiating methionine |
| Tyr 261 | Asp 261 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49796.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 661.7 | |
| All* | Total formula weight | 50458.5 |
