2EWP
Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domaind with tamoxifen analog GSK5182
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Estrogen-related receptor gamma | polymer | 226 | 25657.8 | 5 | UniProt (P62508) Pfam (PF00104) In PDB | Homo sapiens (human) | Estrogen receptor-related protein 3, ERR gamma-2 |
2 | A, B, C, D, E | (Z)-4-(1-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-HYDROXY-2-PHENYLPENT-1-ENYL)PHENOL | non-polymer | 417.5 | 5 | Chemie (TXF) | |||
3 | water | water | 18.0 | 412 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 128289.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 2087.7 | |
All* | Total formula weight | 130376.8 |