2EWP

Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domaind with tamoxifen analog GSK5182

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Estrogen-related receptor gamma	polymer	226	25657.8	5	UniProt (P62508) Pfam (PF00104)	Homo sapiens (human)	Estrogen receptor-related protein 3, ERR gamma-2
2	F, G, H, I, J (A, B, C, D, E)	(Z)-4-(1-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-HYDROXY-2-PHENYLPENT-1-ENYL)PHENOL	non-polymer		417.5	5	Chemie (TXF)
3	K, L, M, N, O (A, B, C, D, E)	water	water		18.0	412	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	128289.1
Non-Polymers*	Number of molecules	5
	Total formula weight	2087.7
All*	Total formula weight	130376.8

*Water molecules are not included.