2ETZ
The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase ITK/TSK | polymer | 109 | 12560.2 | 1 | UniProt (Q03526) Pfam (PF00017) | Mus musculus (house mouse) | T-cell-specific kinase, IL-2-inducible T-cell kinase, Kinase EMT, Kinase TLK, Itk |
| 2 | B (B) | Lymphocyte cytosolic protein 2 phosphopeptide fragment | polymer | 8 | 794.7 | 1 | UniProt (Q60787) | SH2 domain-containing leucocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, SLP76 |
Sequence modifications
A: 4 - 110 (UniProt: Q03526)
B: 119 - 124 (UniProt: Q60787)
| PDB | External Database | Details |
|---|---|---|
| Gly 111 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Ptr 121 | Tyr 145 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13355.0 | |
| All* | Total formula weight | 13355.0 |
