2ETK
Crystal Structure of ROCK 1 bound to hydroxyfasudil
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Rho-associated protein kinase 1 | polymer | 415 | 48012.3 | 2 | UniProt (Q13464) Pfam (PF00069) In PDB | Homo sapiens (human) | Rho-associated, coiled-coil containing protein kinase 1, p160 ROCK-1, p160ROCK |
2 | A, B | 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE | non-polymer | 307.4 | 2 | Chemie (HFS) |
Sequence modifications
A, B: 6 - 415 (UniProt: Q13464)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | cloning artifact |
Ser 2 | - | cloning artifact |
Leu 3 | - | cloning artifact |
His 4 | - | cloning artifact |
Met 5 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 96024.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 614.7 | |
All* | Total formula weight | 96639.3 |