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2EQB

Crystal structure of the Rab GTPase Sec4p, the Sec2p GEF domain, and phosphate complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ras-related protein SEC4polymer17419447.21UniProt (P07560)
Pfam (PF00071)
Saccharomyces cerevisiae (baker's yeast)Suppressor of RHO3 protein 6, Rab GTPase Sec4p
2B, C
(B, C)
Rab guanine nucleotide exchange factor SEC2polymer9711391.62UniProt (P17065)
Pfam (PF06428)
Saccharomyces cerevisiae (baker's yeast)GDP-GTP exchange factor SEC2
3D, E
(A, C)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
4F, G, H
(A, B, C)
waterwater18.0114Chemie (HOH)
Sequence modifications
A: 19 - 187 (UniProt: P07560)
PDBExternal DatabaseDetails
Gly 14-cloning artifact
Pro 15-cloning artifact
Leu 16-cloning artifact
Gly 17-cloning artifact
Ser 18-cloning artifact
B, C: 51 - 142 (UniProt: P17065)
PDBExternal DatabaseDetails
Gly 46-cloning artifact
Pro 47-cloning artifact
Leu 48-cloning artifact
Gly 49-cloning artifact
Ser 50-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight42230.3
Non-Polymers*Number of molecules2
Total formula weight189.9
All*Total formula weight42420.3
*Water molecules are not included.

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PDB entries from 2025-07-02

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