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2EQB

Crystal structure of the Rab GTPase Sec4p, the Sec2p GEF domain, and phosphate complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
B0005085molecular_functionguanyl-nucleotide exchange factor activity
C0005085molecular_functionguanyl-nucleotide exchange factor activity
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE PO4 A 201
ChainResidue
AASP28
ASER29
AGLY30
AVAL31
AGLY32
ALYS33
ASER34
AHOH204
AHOH227

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PO4 C 202
ChainResidue
BLYS56
BASN60
BLYS63
CARG120
CLYS123
CHOH212

Functional Information from PROSITE/UniProt
site_idPS00675
Number of Residues14
DetailsSIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. ILLiGDSGVGKscL
ChainResidueDetails
AILE23-LEU36

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AGLY27
AASP75

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASN133

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
AGLN79

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
AGLY30

226707

PDB entries from 2024-10-30

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