2ELB

Crystal Structure of the BAR-PH domain of human APPL1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adapter protein containing PH domain, PTB domain and leucine zipper motif 1	polymer	396	45987.1	1	UniProt (Q9UKG1) Pfam (PF16746) Pfam (PF00169)	Homo sapiens (human)	APPL1, Dip13 alpha, DCC-interacting protein 13 alpha

Sequence modifications

A: 1 - 376 (UniProt: Q9UKG1)

PDB	External Database	Details
Mse -19	-	cloning artifact
Gly -18	-	cloning artifact
Ser -17	-	cloning artifact
Ser -16	-	cloning artifact
His -15	-	cloning artifact
His -14	-	cloning artifact
His -13	-	cloning artifact
His -12	-	cloning artifact
His -11	-	cloning artifact
His -10	-	cloning artifact
Ser -9	-	cloning artifact
Ser -8	-	cloning artifact
Gly -7	-	cloning artifact
Leu -6	-	cloning artifact
Val -5	-	cloning artifact
Pro -4	-	cloning artifact
Arg -3	-	cloning artifact
Gly -2	-	cloning artifact
Ser -1	-	cloning artifact
His 0	-	cloning artifact
Mse 1	Met 1	modified residue
Mse 37	Met 37	modified residue
Mse 44	Met 44	modified residue
Mse 82	Met 82	modified residue
Mse 111	Met 111	modified residue
Mse 112	Met 112	modified residue
Mse 178	Met 178	modified residue
Mse 179	Met 179	modified residue
Mse 204	Met 204	modified residue
Mse 213	Met 213	modified residue
Mse 240	Met 240	modified residue
Mse 247	Met 247	modified residue
Asp 270	Lys 270	conflict
Mse 310	Met 310	modified residue
Mse 323	Met 323	modified residue
Mse 331	Met 331	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45987.1
All*	Total formula weight	45987.1

*Water molecules are not included.