2E6Y
Covalent complex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Orotidine 5'-phosphate decarboxylase | polymer | 252 | 27379.4 | 2 | UniProt (O26232) Pfam (PF00215) | Methanothermobacter thermautotrophicus | OMP decarboxylase, OMPDCase, OMPdecase, Orotidine 5'-monophosphate decarboxylase, ODCase |
| 2 | C, G (A, B) | URIDINE-5'-MONOPHOSPHATE | non-polymer | 324.2 | 2 | Chemie (U5P) | |||
| 3 | D, E, F, H (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 228 (UniProt: O26232)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
| Pro 101 | Arg 101 | SEE REMARK 999 |
| Arg 226 | Leu 226 | engineered mutation |
| Ile 227 | Asn 227 | engineered mutation |
| Glu 229 | - | cloning artifact |
| Asp 230 | - | cloning artifact |
| Pro 231 | - | cloning artifact |
| Ala 232 | - | cloning artifact |
| Ala 233 | - | cloning artifact |
| Asn 234 | - | cloning artifact |
| Lys 235 | - | cloning artifact |
| Ala 236 | - | cloning artifact |
| Arg 237 | - | cloning artifact |
| Lys 238 | - | cloning artifact |
| Glu 239 | - | cloning artifact |
| Ala 240 | - | cloning artifact |
| Glu 241 | - | cloning artifact |
| Leu 242 | - | cloning artifact |
| Ala 243 | - | cloning artifact |
| Ala 244 | - | cloning artifact |
| Ala 245 | - | cloning artifact |
| Thr 246 | - | cloning artifact |
| Ala 247 | - | cloning artifact |
| Glu 248 | - | cloning artifact |
| Gln 249 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54758.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1016.7 | |
| All* | Total formula weight | 55775.5 |
