2E3T
Crystal structure of rat xanthine oxidoreductase mutant (W335A and F336L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Xanthine dehydrogenase/oxidase | polymer | 1331 | 146265.2 | 2 | UniProt (P22985) Pfam (PF00111) Pfam (PF01799) Pfam (PF00941) Pfam (PF03450) Pfam (PF01315) Pfam (PF02738) Pfam (PF20256) | Rattus norvegicus (Norway rat) | |
| 2 | C, P (A, B) | BICARBONATE ION | non-polymer | 61.0 | 2 | Chemie (BCT) | |||
| 3 | D, E, F, G, H... (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 11 | Chemie (PO4) | |||
| 4 | J, K, V, W (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | L, M, X, Y (A, B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 4 | Chemie (FES) | |||
| 6 | N, Z (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 7 | AA, O (B, A) | URIC ACID | non-polymer | 168.1 | 2 | Chemie (URC) | |||
| 8 | BA, CA (A, B) | water | water | 18.0 | 1391 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 1331 (UniProt: P22985)
| PDB | External Database | Details |
|---|---|---|
| Ala 335 | Trp 334 | engineered mutation |
| Leu 336 | Phe 335 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 292530.4 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 3937.6 | |
| All* | Total formula weight | 296468.0 |
