2E3K
Crystal structure of the human Brd2 second bromodomain in complexed with the acetylated histone H4 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bromodomain-containing protein 2 | polymer | 112 | 13184.1 | 4 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (human) | Protein RING3, O27.1.1 |
| 2 | E, F (Q, R) | 15-mer peptide from Histone H4 | polymer | 15 | 1372.5 | 2 | UniProt (P02309) | ||
| 3 | G, H, I, J, K... (A, B, C, D, Q...) | water | water | 18.0 | 412 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 348 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Gly 344 | - | expression tag |
| Ser 345 | - | expression tag |
| His 346 | - | expression tag |
| Met 347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 55481.6 | |
| All* | Total formula weight | 55481.6 |
