2DYP

Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HLA class I histocompatibility antigen, alpha chain G	polymer	277	32017.5	1	UniProt (P17693) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	HLA G antigen
2	B (B)	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C (C)	9 Mer Peptide From Histone H2A.x	polymer	9	1148.4	1	UniProt (P16104)
4	D (D)	Leukocyte immunoglobulin-like receptor subfamily B member 2	polymer	196	21896.7	1	UniProt (Q8N423) Pfam (PF13895)	Homo sapiens (human)	Leukocyte immunoglobulin-like receptor 2, LIR-2, Immunoglobulin- like transcript 4, ILT-4, Monocyte/macrophage immunoglobulin-like receptor 10, MIR-10, CD85d antigen
5	E, F, G, H (A, B, C, D)	water	water		18.0	86	Chemie (HOH)

Sequence modifications

A: 1 - 276 (UniProt: P17693)

PDB	External Database	Details
Met 0	-	initiating methionine
Ser 42	Cys 66	engineered mutation

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

D: 1 - 196 (UniProt: Q8N423)

PDB	External Database	Details
Arg 61	His 84	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66942.0
All*	Total formula weight	66942.0

*Water molecules are not included.