2DVV
Crystal structure of the second bromodomain of the human Brd2 protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 2 | polymer | 112 | 13184.1 | 1 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (human) | BRD2, RING3 protein, O27.1.1 |
| 2 | B (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 3 | C (A) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A: 348 - 455 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| His 3 | - | cloning artifact |
| Met 4 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13184.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 238.3 | |
| All* | Total formula weight | 13422.4 |
