2DV3
Crystal structure of Leu65 to Arg mutant of Diphthine synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | diphthine synthase | polymer | 265 | 29657.4 | 2 | UniProt (O58456) | Pyrococcus horikoshii | Diphthamide biosynthesis methyltransferase |
| 2 | C (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 3 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (177678424) PubChem (52224398) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (6419189) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (164157219) PubChem (118374891) PubChem (118560068) PubChem (5284331) PubChem (126969526) PubChem (129105892) PubChem (71170554) PubChem (143518505) PubChem (154578335) PubChem (13231890) PubChem (163054214) PubChem (163335525) | |||
| 4 | E (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | F, G (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 6 | H (B) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) PubChem (284) | |||
| 7 | I, J (A, B) | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 265 (UniProt: O58456)
| PDB | External Database | Details |
|---|---|---|
| Arg 65 | Leu 65 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59314.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 673.1 | |
| All* | Total formula weight | 59987.9 |
