Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004164 | molecular_function | diphthine synthase activity |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0017183 | biological_process | protein histidyl modification to diphthamide |
| A | 0032259 | biological_process | methylation |
| B | 0004164 | molecular_function | diphthine synthase activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0017183 | biological_process | protein histidyl modification to diphthamide |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1301 |
| Chain | Residue |
| A | TYR117 |
| A | HOH1374 |
| B | HOH1503 |
| B | HOH1507 |
| B | HOH1516 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1302 |
| Chain | Residue |
| B | ARG46 |
| B | TYR128 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE SAH A 1300 |
| Chain | Residue |
| A | SER37 |
| A | ASP87 |
| A | VAL90 |
| A | SER115 |
| A | ILE116 |
| A | PHE165 |
| A | LEU166 |
| A | ARG208 |
| A | ALA209 |
| A | PRO233 |
| A | HIS234 |
| A | ILE235 |
| A | HOH1311 |
| A | HOH1328 |
| A | HOH1409 |
| A | LEU10 |
| A | THR36 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1401 |
| Chain | Residue |
| B | LEU38 |
| B | MET39 |
| B | THR42 |
| B | THR43 |
| B | LEU44 |
| B | HOH1565 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1402 |
| Chain | Residue |
| B | THR92 |
| B | ALA134 |
| B | THR135 |
| B | HOH1543 |
| B | HOH1566 |
| B | HOH1676 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 1501 |
| Chain | Residue |
| B | ARG46 |
| B | LYS129 |
| B | HIS243 |
| B | HOH1548 |
| B | HOH1667 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LEU10 | |
| B | VAL90 | |
| B | SER115 | |
| B | LEU166 | |
| B | ALA209 | |
| B | HIS234 | |
| A | ASP87 | |
| A | VAL90 | |
| A | SER115 | |
| A | LEU166 | |
| A | ALA209 | |
| A | HIS234 | |
| B | LEU10 | |
| B | ASP87 | |
