2DSR
Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Insulin-like growth factor-binding protein 4 | polymer | 82 | 9118.4 | 1 | UniProt (P22692) Pfam (PF00086) | Homo sapiens (human) | IGFBP-4, IBP-4, IGF-binding protein 4 |
| 2 | B (B) | Insulin-like growth factor-binding protein 4 | polymer | 80 | 8498.1 | 1 | UniProt (P22692) Pfam (PF00219) | Homo sapiens (human) | IGFBP-4, IBP-4, IGF-binding protein 4 |
| 3 | C (I) | Insulin-like growth factor IB | polymer | 70 | 7663.8 | 1 | UniProt (P05019) Pfam (PF00049) | Homo sapiens (human) | IGF-IB, Somatomedin C, Mechano growth factor, MGF |
| 4 | D, E, F (G, B, I) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 25280.2 | |
| All* | Total formula weight | 25280.2 |
